The role of tranexamic acid in breast and body contouring surgery: a review of the literature

Background: Postoperative seroma and haematoma are two of the most common complications follow-ing large surface area surgeries. A review literature was performed to evaluate evidence for use tranexamic acid in reducing postoperative formation breast surgery body contouring surgery. Methods search using MEDLINE, Cochrane Database Systematic Review, Central Register Controlled Trials (CENTRAL), Abstracts Reviews Ef-fect (DARE) PubMed English from 1 Jan 1990–30 Mar 2020. The terms ‘TXA’, ‘breast reduction’, ‘mammaplasty’, implants’, implantation’, reconstruction’, ‘mastectomy’, ‘tissue ex-pansion’, ‘body contouring’, ‘breast’ ‘abdominoplasty’ were used alone combination. Results: total six articles found including three randomised controlled trials, cohort studies one retrospective study. Two ongoing trials on Con-trolled (CENTRAL). No systematic reviews found. Conclusion: Literature surrounding TXA is sparse com-pared what available other surgical sub-specialties. shows promising results with controlling haematoma, drain output minimal morbidity these patient groups.